RESEARCH PROJECTS : |
KBIPER right from its inception in 1995 had
the necessary infrastructure and expertise
to conduct wide variety of research projects
in the field of pharmacy. The basic aim of
establishing research facility is to provide
facilities for doctoral level research work
of the faculty and to cater to the needs of
pharma industries. The areas of research which
our institute can handle with full expertise
include:
|
 |
| 1. |
Synthesis
of new drug molecules and drug intermediates.
Alternate procedures to existing synthetic steps
in synthesis of drugs can also be developed
to improve the cost factor in bulk drug manufacturing. |
|
|
| 2. |
Animal
studies pertaining to screening and evaluation of
CNS disorders: Psychosis, depression, anxiety, Alzheimer’s
disease, analgesics, anti-inflammatory agents
GIT disorders: Gastric and duodenal ulcers, diarrohea,
constipation
Respiratory disorders: Bronchial asthama
Allergic disorders: Adaptogenic and anti-oxidant drugs
CVS disorders: Hypertension and atherosclerosis
Liver disorders: Hepatoprotective agents
Glaucoma |
| 3. |
Conduting Bioassay of drugs like Heparin, Leutinising
Hormone, Follicle Stimulating Hormone as per the official
standards. |
| 4. |
Isolate
tissue experiments to study the activity of drugs on
various receptors such as adrenergic receptors (alfa1,
alfa2, bita1, bita2), Dopaminergic receptors, Histaminergic
receptors, 5-Hydroxytryptaminergic, purinergic and Cholinergic
receptors. |
| 5. |
Acute,
subacute and chronic toxicity studies of new and the
existing drugs or drug formulations as per the Schedule
‘Y’. |
| 6. |
Development of drug formulations such as suspensions,
emulsions, ophthalmic products, tablets, sustained release
formulations, ointment, gels etc. |
| 7. |
Stability testing studies for different formulations. |
| 8. |
Analytical method development for new drugs and formulations. |
| 9. |
Development of tissue culture techniques of different
herbal drugs |
| 10. |
Microbiological assays for antibacterial agents. |
| 11. |
Pyrogen testing of the drugs by official methods specified
in IP,BP and USP. |
| 12. |
Isolation and characterization of degradation products
of different official drugs. |
| 13. |
Degradation kinetics of various drugs under different
forced conditions like light, acidic and alkaline medium,
oxidative medium etc. as per ICH guidelines. |
| 14. |
Validation
of different analytical instruments as per FDA guidelines. |
| Research Project Done: |
Over
the period of nine years of existence of this institute,
KBIPER has been able to support different industries
with its expertise in research. Some of these projects
include: |
| 1. |
Evaluation
of polyherbal drug formulations for its anti asthamatic
potential – sponsored by Himalaya Drug Company,
Banglore. |
| 2. |
Evaluation
of new new drugs for the treatment of depression, pain,
psychosis, emesis, inflammation – sponsored by
Sun Pharmaceuticals, Baroda. |
| 3. |
Evaluation
of newly synthesized anti-ulcer agents, anti-diarroheals
and laxatives – sponsored by Kopran Pharmaceuticals
Ltd, Mumbai. |
| 4. |
Acute
toxicity studies of newly synthesized agents according
to Schedule Y – sponsored by Kopran Pharmaceuticals
Ltd, Mumbai. |
| 5. |
Sub
acute toxicity studies according to Schedule Y regulations
of a new drug – sponsored by Core Healthcare Ltd,
Ahmedabad. |
| 6. |
Bioassay
of Heparin as per Indian Pharmacopoeia, 1996 –
sponsored by Core Healthcare Ltd, Ahmedabad. |
| |
Estimation
of Ascorbic acid content in the formulation. |
| |
The
Research Center is known for its authentic research
activities. A gradual increase in the industry-sponsored
projects is a proof of authentic and quality work. |
| |
Any
queries regarding the research activities are welcomed. |
| |
For
the preparations of documents for the export of drugs
to different countries like Bangladesh, Sri Lanka, Russia,
U.K., African countries, U.S.A. and other countries
the institute will be able to lend its expertise. |
